Kyoshiro Hiki
The University of Tokyo
Dr. Kyoshiro Hiki is a lecturer at the University of Tokyo. He received his PhD from the University of Tokyo in 2016 and subsequently worked at the National Institute for Environmental Studies as a postdoctoral fellow and senior researcher. His research interests include ecotoxicology and ecological risk assessment, with a focus on sediment contamination, urban runoff, and the application of molecular technologies. Following his master’s work, he has evaluated the toxicity of road dust and road runoff-related chemicals on aquatic and benthic organisms. Since the discovery of 6PPD-quinone as the causative agent for acute die-offs of coho salmon, he has further investigated the toxicity of 6PPD, 6PPD-quinone, and related chemicals to aquatic organisms, while also pursuing the underlying mechanisms of 6PPD-quinone toxicity.
Session 8 – Mechanisms and Toxicity of Tire-Derived Chemicals
- Mechanistic Insights Into 6PPD-Quinone Toxicity Using Brain- and Gill-Derived Rainbow Trout (Oncorhynchus mykiss) Cell Lines as New Approach Methodologies (NAMs)
Speaker: Anna Toso - Unraveling Species-Specific Sensitivity to 6PPD-Quinone Across Four Fish Species Using Whole Transcriptome Analyses
Speaker: Markus Brinkmann - Transcriptome and Causality Analysis of Rainbow Trout Gill Cells Exposed to 6PPD-Q and Its Metabolite
Speaker: Kyoshiro Hiki - From Molecular Stress to Ecosystem Functioning: Assessing the Ecotoxicological Impacts of 6PPD-Quinone on Alpine Freshwater Species
Speaker: Emilie Réalis - Impact of Ingested Tire-Derived p-Phenylenediamines (PPDs) and PPD-Quinones on the Gut
Speaker: Göksu Celik